Every ingredient in TestoPrime is proven to help increase testosterone levels naturally and is backed by clinical studies from trusted sources. Learn more about how TestoPrimes' ingredients are proven to work.
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Year
Study Title
2009
The Role and Molecular Mechanism of D-Aspartic Acid in the Release and Synthesis of LH and Testosterone in Humans.
Summary: D-Aspartic Acid increases testosterone levels by stimulating the release of luteinizing hormone (LH) and enhancing the synthesis of testosterone in the testes.
2013
Occurrence of D-Aspartic Acid and N-Methyl-D-Aspartic Acid in Rat Neuroendocrine Tissues and Their Role in the Modulation of Luteinizing Hormone and Growth Hormone Release.
Summary: D-Aspartic Acid plays a key role in stimulating the release and synthesis of luteinizing hormone (LH) and testosterone in the endocrine system, as shown by its accumulation and activity in the pituitary and testes.
2013
Evaluation of in vivo supplementation of 2660 mg D-aspartic acid and 200 mg ubiquinol and 10 mg zinc on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study.
Summary: DAA + ubiquinol + zinc improved infertile males’ testosterone levels.
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Year
Study Title
2013
Antifatigue Effects of Panax Ginseng C.A. Meyer: a Randomised, Double-Blind, Placebo-Controlled Trial.
Summary: Ginseng helps increase testosterone levels by enhancing testicular steroidogenesis and activating the hypothalamic-pituitary-gonadal axis.
2013
Ginseng and Male Reproductive Function.
Summary: Ginseng increases testosterone and LH; 5% dietary supplementation shows significant effects. Clinical study: Asian ginseng extract increased total/free testosterone, FSH, LH in 66 men.
2013
Hormonal, Histological, and Comparative Study of the Effect of Pure Ginseng on Testicular Function in the Breeding/Non-Breeding Season of Rams in Basrah.
Summary: Powdered Panax ginseng increased testosterone and stimulated spermatogenesis.
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Year
Study Title
2013
Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study.
Summary: Ginseng helps increase testosterone levels by enhancing testicular steroidogenesis and activating the hypothalamic-pituitary-gonadal axis.
2013
A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha ( Withania somnifera) in Aging, Overweight Males.
Summary: Randomized crossover trial: Ashwagandha boosted testosterone ~14.7% vs placebo.
2013
Withania somnifera (Ashwagandha) supplementation: a review of its mechanisms, health benefits, and role in sports performance.
Summary: Ashwagandha consistently increases testosterone in healthy adults.
2013
Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
Summary: Standardized root extract significantly raised serum testosterone in men.
2013
Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.
Summary: Study found Ashwagandha increased muscle mass/strength alongside testosterone.
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Year
Study Title
2020
Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials.
Summary: Clinical trial showed significant total testosterone increase with fenugreek extract.
2020
Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: A randomized controlled pilot study.
Summary: Fenugreek glycoside supplementation increased free testosterone compared to placebo.
2020
Safety and Efficacy of Furosap®, a Patented Trigonella foenum-graecum Seed Extract, in Boosting Testosterone Level, Reproductive Health and Mood Alleviation in Male Volunteers.
Summary: Furosap® (standardized fenugreek extract) improved testosterone, sperm, mood in men.
2020
Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study.
Summary: Testofen® increased testosterone and alleviated androgen decline symptoms in aging men.
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Year
Study Title
2013
Effect of Green Tea Extract on Fat Oxidation at Rest and during Exercise: Evidence of Efficacy and Proposed Mechanisms.
Summary: Green tea may help increase testosterone levels by reducing oxidative stress and modulating hormone-regulating enzymes, which supports healthier testosterone balance.
2008
Does regular consumption of green tea influence expression of vascular endothelial growth factor and its receptor in aged rat erectile tissue? Possible implications for vasculogenic erectile dysfunction progression.
Summary: Long-term tea intake correlated with increased testosterone in older men.
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Year
Study Title
2014
Effects of Pomegranate Extract on Blood Flow and Running Time to Exhaustion.
Summary: Pomegranate helps increase testosterone levels by reducing oxidative stress and enhancing the activity of key steroidogenic enzymes involved in testosterone production.
2014
Protective effects of pomegranate (Punica granatum) juice on testes against carbon tetrachloride intoxication in rats.
Summary: Pomegranate juice raised testosterone, LH, FSH after testicular injury.
2012
Pomegranate juice intake enhances salivary testosterone levels and improves mood and well being in healthy men and women.
Summary: Pomegranate juice increased salivary testosterone by ~24% in humans.
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Year
Study Title
1996
Dietary Zinc Deficiency Alters 5 Alpha-Reduction and Aromatization of Testosterone and Androgen and Estrogen Receptors in Rat Liver.
Summary: Zinc helps increase testosterone levels by supporting the production of luteinizing hormone and maintaining normal testicular function, with deficiency leading to significant reductions in serum testosterone.
2023
Correlation between serum zinc and testosterone: A systematic review.
Summary: Zinc deficiency lowers testosterone; supplementation improves levels.
2023
Effect of zinc administration on plasma testosterone, dihydrotestosterone, and sperm count.
Summary: Zinc therapy in infertile men increased testosterone and DHT.
2023
Low serum zinc concentration is associated with low serum testosterone but not erectile function.
Summary: Low serum zinc correlated with low testosterone.
2018
A novel role for zinc transporter 8 in the facilitation of zinc accumulation and regulation of testosterone synthesis in Leydig cells of human and mouse testicles.
Summary: ZnT8 transporter involvement suggests zinc’s important role in testicular testosterone synthesis.
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Year
Study Title
1984
Increased Target Tissue Uptake of, and Sensitivity to, Testosterone in the Vitamin B6 Deficient Rat.
Summary: Vitamin B6 helps increase testosterone levels by influencing androgen receptor binding and modulating the hormonal environment necessary for testosterone action and synthesis.
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Year
Study Title
2009
Effects of pantothenic acid on testicular function in male rats.
Summary: Pantothenic acid (Vitamin B5) essential for testicular endocrinology & sperm motility.
2022
Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5.
Summary: Niacin/B5 is critical in hormone synthesis pathways, including testosterone.
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Year
Study Title
2010
Effect of Vitamin D Supplementation on Testosterone Levels in Men.
Summary: Vitamin D helps increase testosterone levels, as supplementation in vitamin D-deficient men led to a significant rise in total, bioactive, and free testosterone levels over 12 months.
2022
Association Between Vitamin D Deficiency and Testosterone Levels in Adult Males: A Systematic Review.
Summary: Mendelian randomization study shows genetically lower vitamin D correlates with lower testosterone.
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Year
Study Title
2015
Retention of Testicular Integrity and Testosterone Levels upon Ingestion of Garlic Cloves (Allium Sativum) in the Sprague-Dawley Rat.
Summary: Garlic helps increase testosterone levels by stimulating luteinizing hormone production and enhancing testicular function through its antioxidant and cholesterol-lowering effects.
2001
Garlic supplementation increases testicular testosterone and decreases plasma corticosterone in rats fed a high protein diet.
Summary: Garlic supplementation increases testicular testosterone by stimulating LH and lowering corticosterone.
2021
Impacts of garlic extract on testicular oxidative stress and sperm characteristics in type 1 and 2 diabetic rats: An experimental study.
Summary: Garlic improves testicular oxidative stress and sperm quality, and increases testosterone.
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Year
Study Title
2018
Diverged Effects of Piperine on Testicular Development: Stimulating Leydig Cell Development but Inhibiting Spermatogenesis in Rats.
Summary: Piperine (from black pepper) increased serum testosterone and affected Leydig cell function.
2020
The Effect of Black Pepper Fruits (Piper nigrum L.) on the Increase of Erection.
Summary: Black pepper extract enhanced fertility and testosterone levels.
2020
Piperine-A Major Principle of Black Pepper: A Review of Its Bioactivity and Studies.
Summary: Black pepper extract boosted sex hormones (T, FSH, LH) and Leydig cell size.
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We are so confident in the unique combination of ingredients inside each capsule of TestoPrime that we offer a 100%, no questions asked, no hassle whatsoever, 60-day guarantee.
How can we give such a ludicrous guarantee? Simple. We have spent 100s of $1000s of dollars in 3rd party testing and re-testing to prove that our formula works with stellar results.
We do not cut corners with our formula. We do not hide our ingredients as a “proprietary blend.” We ensure each small batch of TestoPrime is made with the highest standards in a GMP-certified facility with FDA-approved ingredients.
However, we also understand no two people are the same.
That’s why if you happen to fall in the small group of men (less than 2%) who do not see and feel the positive results of having more testosterone, then return your order and send us an email, and we will refund your investment, every single penny, and won’t hold it against you.
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